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Review: Portopulmonary hypertension: challenges in diagnosis and managementPulmonary and Critical Care Unit, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02114, USA, abwaxman{at}partners.org
Patrick J. Troy Pulmonary and Critical Care Unit, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02114, USA Portopulmonary hypertension is defined as the combination of pulmonary arterial hypertension with portal hypertension and presents management complications in patients awaiting liver transplantation. The combination of these vascular disorders has a marked impact on mortality. At present the recommendations for management are limited because of the paucity of definitive clinical trials. We have reviewed the available data on prevalence, diagnosis and treatment. It is clearly time to more formally approach the study of this patient population.
Key Words: pulmonary hypertension portal hypertension liver disease portopulmonary hypertension vasodilators
This version was published on September
1, 2009 Therapeutic Advances in Gastroenterology, Vol. 2, No. 5,
281-286 (2009) |
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